Matrix metalloproteinases and their tissue inhibitors as upcoming biomarker signatures of connective tissue diseases-related interstitial lung disease: towards an earlier and accurate diagnosis
MMPs and TIMPs form combinatorial biomarker signatures with clinical value for non-invasive, early, and accurate diagnosis of RA-ILD<sup>+</sup> and SSc-ILD<sup>+</sup>, constituting promising screening tools in clinical practice.
Authors
- Raquel López‐Mejías (ORCID: https://orcid.org/0000-0003-0548-2689)
- Belén Atienza‐Mateo (ORCID: https://orcid.org/0000-0001-7119-0786)
- M. Sebastián Mora-Gil
- Verónica Pulito‐Cueto (ORCID: https://orcid.org/0000-0002-3534-8467)
- David Iturbe‐Fernández (ORCID: https://orcid.org/0000-0002-5241-266X)
- Sheila Izquierdo Cuervo
- Víctor Manuel Mora Cuesta (ORCID: https://orcid.org/0000-0002-8161-0462)
- Ricardo Blanco (ORCID: https://orcid.org/0000-0003-2344-2285)
- J. Batista-Liz (ORCID: https://orcid.org/0009-0002-5315-9202)
- C. Aguirre Portilla
Institutions
- Marqués de Valdecilla University Hospital (ES)
- Instituto de Investigación Marqués de Valdecilla (ES)
Publication Details
- Journal
- Molecular Medicine
- Published
- 2025-02-20
- DOI
- https://doi.org/10.1186/s10020-025-01128-2
- Citations
- 13
- Primary Topic
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Type
- article
- Field-Weighted Citation Impact
- 19.74