A Candidate Ac3-S-LPS Vaccine Against S. flexneri 1b, 2a, 3a, 6, and Y Activates Long-Lived Systemic and Mucosal Immune Responses in Healthy Volunteers: Results of an Open-Label, Randomized Phase 2 Clinical Trial

the tolerability of PLVF and the pronounced humoral immune response allow us to proceed to the phase 3 clinical trial stage.

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Publication Details

Journal
Vaccines
Published
2025-02-20
DOI
https://doi.org/10.3390/vaccines13030209
Primary Topic
Clostridium difficile and Clostridium perfringens research
Type
article
Field-Weighted Citation Impact
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article

A Candidate Ac3-S-LPS Vaccine Against S. flexneri 1b, 2a, 3a, 6, and Y Activates Long-Lived Systemic and Mucosal Immune Responses in Healthy Volunteers: Results of an Open-Label, Randomized Phase 2 Clinical Trial

Victor V. Romanenko, M.E. Golovina, Alexander L. Kovalchuk, Vladimir A. Ledov et al.
Vaccines
Clostridium difficile and Clostridium perfringens research
article

A Candidate Ac3-S-LPS Vaccine Against S. flexneri 1b, 2a, 3a, 6, and Y Activates Long-Lived Systemic and Mucosal Immune Responses in Healthy Volunteers: Results of an Open-Label, Randomized Phase 2 Clinical Trial

Victor V. Romanenko, M.E. Golovina, Alexander L. Kovalchuk, Vladimir A. Ledov, Biana I. Alkhazova, Petr G. Aparin
article en

Abstract

the tolerability of PLVF and the pronounced humoral immune response allow us to proceed to the phase 3 clinical trial stage.

VaccinesVol. 13(3)
InSysBio (Russia) (RU), Federal Medical-Biological Agency (RU)
Good health and well-being
Openalex Percentile: Top 95%
Clostridium difficile and Clostridium perfringens research
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