Dual Sustained-Release BMP7-Nanoparticle Hydrogel Scaffolds for Enhanced BMSC Neuronal Differentiation and Spinal Cord Injury Repair

The BMP7-NPs/Gel-MA scaffold provides sustained delivery of BMP-7, effectively directing BMSC differentiation into neuron-like cells while avoiding glial commitment. Combined with BMSCs, it offers a promising therapeutic strategy for SCI repair.

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Publication Details

Journal
Spine
Published
2025-02-18
DOI
https://doi.org/10.1097/brs.0000000000005307
Citations
3
Primary Topic
Tissue Engineering and Regenerative Medicine
Type
article
Field-Weighted Citation Impact
6.02
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article

Dual Sustained-Release BMP7-Nanoparticle Hydrogel Scaffolds for Enhanced BMSC Neuronal Differentiation and Spinal Cord Injury Repair

Shiyuan Huang, Kuanxin Li, Xudong Sun, Heng Zhang et al.
3 citations
Spine
Tissue Engineering and Regenerative Medicine
6.02
article

Dual Sustained-Release BMP7-Nanoparticle Hydrogel Scaffolds for Enhanced BMSC Neuronal Differentiation and Spinal Cord Injury Repair

Shiyuan Huang, Kuanxin Li, Xudong Sun, Heng Zhang, Xuyi Wang
article en
3 citations

Abstract

The BMP7-NPs/Gel-MA scaffold provides sustained delivery of BMP-7, effectively directing BMSC differentiation into neuron-like cells while avoiding glial commitment. Combined with BMSCs, it offers a promising therapeutic strategy for SCI repair.

SpineVol. 50(9)
Bengbu Medical College (CN), First Affiliated Hospital of Bengbu Medical College (CN)
Clean water and sanitation
Openalex Percentile: Top 5%
Tissue Engineering and Regenerative Medicine
6.02
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