Dihydromyricetin Improves Myocardial Functioning by Influencing Autophagy Through SNHG17/Mir 34a/SIDT2 Axis
DHM improves cardiac function and mitigates DCM progression by targeting the SNHG17/miR-34a/SIDT2 regulatory axis, thereby reducing inflammation, fibrosis, and autophagy dysregulation. These findings provide mechanistic insights into DHM’s cardioprotective effects, supporting its potential as a therapeutic agent for DCM.
Authors
- Huihui Xie
- Yu Guo (ORCID: https://orcid.org/0000-0002-4490-9764)
- Ziyao Wang (ORCID: https://orcid.org/0009-0001-5591-0576)
- Xiao Yan (ORCID: https://orcid.org/0000-0002-8407-8360)
- Xueliang Zeng
- Hai Xiao
Institutions
- Gannan Medical University (CN)
- First Affiliated Hospital of Gannan Medical University (CN)
Publication Details
- Journal
- Current Molecular Pharmacology
- Published
- 2025-02-20
- DOI
- https://doi.org/10.2174/0118761429374180250212114144
- Citations
- 5
- Primary Topic
- Medicinal plant effects and applications
- Type
- article
- Field-Weighted Citation Impact
- 11.91