A Human Embryonic Stem Cell-derived Neural Stem Cell Senescence Model Triggered by Oxidative Stress
We presented an oxidative stress-induced senescence model of hESC-NSCs and identified key pathways and genes related to D-gal-induced senescence. Our study might offer an alternative approach to investigating human NSCs aging and provide valuable data for understanding the underlying mechanisms of oxidative stress-induced aging.
Authors
- Nianmin Qi (ORCID: https://orcid.org/0000-0002-8580-0925)
- Hui‐Lin Pan (ORCID: https://orcid.org/0000-0001-8444-3770)
- Zhengbing Lyu
- Bao Li (ORCID: https://orcid.org/0000-0002-1030-0467)
- Meng Ji (ORCID: https://orcid.org/0000-0002-1618-572X)
- Yuehong Wu
Institutions
- Zhejiang Sci-Tech University (CN)
- Cell Technology (China) (HK)
Publication Details
- Journal
- Current Stem Cell Research & Therapy
- Published
- 2025-02-20
- DOI
- https://doi.org/10.2174/011574888x365639250214045110
- Citations
- 4
- Primary Topic
- Antioxidants, Aging, Portulaca oleracea
- Type
- article
- Field-Weighted Citation Impact
- 3.64