Gene Therapy and Gene Editing: Current Trends and Future Prospects of Molecular Medicine
Gene therapy and genome editing have emerged as transformative approaches in the management of a diverse range of genetic and acquired diseases. This evaluation offers a thorough examination of the present state and prospects of these innovative technologies. Gene therapy is a prospective approach to the treatment and prevention of a variety of conditions, including complex cancers and inherited genetic disorders, which entail the introduction, removal, or modification of genetic material within a patient's cells. Genome editing, particularly through techniques such as CRISPR-Cas9, enables targeted corrections of genetic defects and opens new possibilities for personalized medicine by allowing for precise modifications at the DNA level. The review addresses the ethical implications, clinical applications, and significant advancements of these technologies. This article endeavors to underscore the substantial influence of gene therapy and genome editing on contemporary medicine by assessing the most recent research and clinical trials, thereby emphasizing their potential to revolutionize disease treatment and management.
Authors
- Sudhir S. Kushwaha (ORCID: https://orcid.org/0000-0003-1882-0958)
- Shashank Shekhar (ORCID: https://orcid.org/0000-0001-8720-6690)
- Shailendra Dwivedi (ORCID: https://orcid.org/0000-0003-2781-1009)
- Akash Bansal (ORCID: https://orcid.org/0000-0002-9574-9326)
- Aniruddha Sen (ORCID: https://orcid.org/0009-0007-5446-2015)
- Vijay Singh (ORCID: https://orcid.org/0009-0000-7283-6008)
- Ruchika Agrawal
Institutions
- Baba Raghav Das Medical College (IN)
- All India Institute of Medical Sciences (IN)
Publication Details
- Journal
- Current Gene Therapy
- Published
- 2025-02-20
- DOI
- https://doi.org/10.2174/0115665232347734250211074241
- Citations
- 6
- Primary Topic
- CRISPR and Genetic Engineering
- Type
- article
- Field-Weighted Citation Impact
- 4.84