Gene Therapy and Gene Editing: Current Trends and Future Prospects of Molecular Medicine

Gene therapy and genome editing have emerged as transformative approaches in the management of a diverse range of genetic and acquired diseases. This evaluation offers a thorough examination of the present state and prospects of these innovative technologies. Gene therapy is a prospective approach to the treatment and prevention of a variety of conditions, including complex cancers and inherited genetic disorders, which entail the introduction, removal, or modification of genetic material within a patient's cells. Genome editing, particularly through techniques such as CRISPR-Cas9, enables targeted corrections of genetic defects and opens new possibilities for personalized medicine by allowing for precise modifications at the DNA level. The review addresses the ethical implications, clinical applications, and significant advancements of these technologies. This article endeavors to underscore the substantial influence of gene therapy and genome editing on contemporary medicine by assessing the most recent research and clinical trials, thereby emphasizing their potential to revolutionize disease treatment and management.

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Publication Details

Journal
Current Gene Therapy
Published
2025-02-20
DOI
https://doi.org/10.2174/0115665232347734250211074241
Citations
6
Primary Topic
CRISPR and Genetic Engineering
Type
article
Field-Weighted Citation Impact
4.84
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Gene Therapy and Gene Editing: Current Trends and Future Prospects of Molecular Medicine

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Gene Therapy and Gene Editing: Current Trends and Future Prospects of Molecular Medicine

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article en
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Abstract

Gene therapy and genome editing have emerged as transformative approaches in the management of a diverse range of genetic and acquired diseases. This evaluation offers a thorough examination of the present state and prospects of these innovative technologies. Gene therapy is a prospective approach to the treatment and prevention of a variety of conditions, including complex cancers and inherited genetic disorders, which entail the introduction, removal, or modification of genetic material within a patient's cells. Genome editing, particularly through techniques such as CRISPR-Cas9, enables targeted corrections of genetic defects and opens new possibilities for personalized medicine by allowing for precise modifications at the DNA level. The review addresses the ethical implications, clinical applications, and significant advancements of these technologies. This article endeavors to underscore the substantial influence of gene therapy and genome editing on contemporary medicine by assessing the most recent research and clinical trials, thereby emphasizing their potential to revolutionize disease treatment and management.

Current Gene TherapyVol. 26(1)
Baba Raghav Das Medical College (IN), All India Institute of Medical Sciences (IN)
Openalex Percentile: Top 5%
CRISPR and Genetic Engineering
4.84
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