DBU-mediated C-C bond formation between Baylis-Hillman Acetates and Active Methylene Compounds
A new reagent system for the formation of C-C bond between the Baylis-Hillman acetates and active methylene compounds (AMCs) were developed. This method provides tri-substituted alkenes as the major product in good yield under neat condition. The reaction proceeds through the SN2ꞌ mechanism to give substituted alkenes in good yields with high stereoselectivity. 1,8-diazabicyclo(5.4.0)undec-7-ene (DBU) act as a unique base which accelerate the rate of the reaction.
Institutions
- North Eastern Regional Institute of Science and Technology (IN)
Publication Details
- Journal
- Indian Journal of Chemistry
- Published
- 2025-02-20
- DOI
- https://doi.org/10.56042/ijc.v64i2.15867
- Primary Topic
- Synthesis of heterocyclic compounds
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- University Grants Commission