Disproportionately Enlarged Subarachnoid-Space Hydrocephalus on MRI in Pathologically Confirmed Progressive Supranuclear Palsy

These findings suggest that DESH and high EI, often considered biomarkers for iNPH, may lack specificity and may be found in a subset of patients with PSP or LBD leading to unnecessary neurosurgery for iNPH.

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Publication Details

Journal
Neurology Clinical Practice
Published
2025-02-20
DOI
https://doi.org/10.1212/cpj.0000000000200431
Citations
8
Primary Topic
Cerebrospinal fluid and hydrocephalus
Type
article
Field-Weighted Citation Impact
5.45
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article

Disproportionately Enlarged Subarachnoid-Space Hydrocephalus on MRI in Pathologically Confirmed Progressive Supranuclear Palsy

Keith A. Josephs, Dennis W. Dickson, Shunsuke Koga, Miki Kawazoe et al.
8 citations
Neurology Clinical Practice
Cerebrospinal fluid and hydrocephalus
5.45
article

Disproportionately Enlarged Subarachnoid-Space Hydrocephalus on MRI in Pathologically Confirmed Progressive Supranuclear Palsy

Keith A. Josephs, Dennis W. Dickson, Shunsuke Koga, Miki Kawazoe, Hiroaki Sekiya, Neill R. Graff‐Radford
article en
8 citations

Abstract

These findings suggest that DESH and high EI, often considered biomarkers for iNPH, may lack specificity and may be found in a subset of patients with PSP or LBD leading to unnecessary neurosurgery for iNPH.

Neurology Clinical PracticeVol. 15(2)
Jacksonville College (US), WinnMed (US), Fukuoka University (JP), Mayo Clinic in Arizona (US), Mayo Clinic in Florida (US)
Openalex Percentile: Top 4%
Cerebrospinal fluid and hydrocephalus
5.45
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