Predictive role of gait parameters and MRI markers in assessing cognitive decline in CSVD patients

This study highlighted the significant relationship between gait performance and cognitive decline in elderly patients with CSVD. In particular, the sit-to-stand component emerged as a robust predictor of cognitive impairment, suggesting its potential as a valuable clinical marker for early detection. The incorporation of gait assessments into routine clinical evaluations can enhance early intervention efforts, improve patient outcomes, and inform healthcare policies. Further longitudinal and multicenter studies are warranted to validate these findings and to explore the underlying mechanisms.