Detection of Novichok and V-Group Nerve Agents by Chemosensors Containing Nile Blue Chromophore

This paper presents the results of experiments aiming for the detection and differentiation of selected nerve agents of the Novichok and V-group using simple strip detectors containing colourimetric indicator, specifically chemosensor Nile Blue A, immobilized in cellulose matrix. In all experimental modifications, the contact of the active zone of the strip detector and respective nerve agent excited an immediate development of significant colouration visible to the naked eye. Alkaline solutions containing various hydroxides, carbonates and bicarbonates, and/or chloramine B were used to demonstrate the relevant reaction. The proposed strip detectors indicate a promising approach towards the development of low-cost, easily portable, and usable means of detection of the respective nerve agents.

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Publication Details

Journal
Chemosensors
Published
2025-02-20
DOI
https://doi.org/10.3390/chemosensors13030077
Citations
2
Primary Topic
Molecular Sensors and Ion Detection
Type
article
Field-Weighted Citation Impact
1.51
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article

Detection of Novichok and V-Group Nerve Agents by Chemosensors Containing Nile Blue Chromophore

Tomáš Dropa, Michal Dymák, Vladimír Pitschmann, M.O. Urban et al.
2 citations
Chemosensors
Molecular Sensors and Ion Detection
1.51
article

Detection of Novichok and V-Group Nerve Agents by Chemosensors Containing Nile Blue Chromophore

Tomáš Dropa, Michal Dymák, Vladimír Pitschmann, M.O. Urban, Markéta Zelenková
article en
2 citations

Abstract

This paper presents the results of experiments aiming for the detection and differentiation of selected nerve agents of the Novichok and V-group using simple strip detectors containing colourimetric indicator, specifically chemosensor Nile Blue A, immobilized in cellulose matrix. In all experimental modifications, the contact of the active zone of the strip detector and respective nerve agent excited an immediate development of significant colouration visible to the naked eye. Alkaline solutions containing various hydroxides, carbonates and bicarbonates, and/or chloramine B were used to demonstrate the relevant reaction. The proposed strip detectors indicate a promising approach towards the development of low-cost, easily portable, and usable means of detection of the respective nerve agents.

ChemosensorsVol. 13(3)
Oritest Group (Czechia) (CZ), National Institute for Nuclear, Chemical and Biological Protection (CZ), Czech Technical University in Prague (CZ)
Openalex Percentile: Top 21%
Molecular Sensors and Ion Detection
1.51
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