Taiwan’s first clinical reports on the surgical effect of high-frequency deep sclerotomy for treating primary open-angle glaucoma

HFDS is a minimally invasive glaucoma surgery (MIGS) that effectively lowers the IOP in patients unresponsive to conventional treatments. This report presents two of Taiwan's first patients with POAG treated by HFDS, showing IOP reductions of 30% and 33.3% over one year with mild corneal endothelial cell loss, which is consistent with previous studies. HFDS demonstrated a significant IOP reduction compared to that in other MIGS techniques and fewer complications than traditional surgeries. Further research should optimize the postoperative management, consider the anatomical differences and pocket healing.