Parallel Networks to Predict <scp>TIMP</scp> and Protease Cell Activity of Nucleus Pulposus Cells Exposed and Not Exposed to Pro‐Inflammatory Cytokines
The PN-Methodology successfully allowed the exploration of the relative dynamics of TIMP and protease regulations in different mechanical, nutritional, and inflammatory environments in the NP. It shall stand as a comprehensive tool to integrate in vitro model results in IVD research and approximate NP cell activities in complex multifactorial environments.
Authors
- Samir E. Witta
- Jérôme Noailly (ORCID: https://orcid.org/0000-0003-3446-7621)
- Laura Baumgartner (ORCID: https://orcid.org/0000-0002-9801-8318)
Institutions
- Universitat Pompeu Fabra (ES)
Publication Details
- Journal
- JOR Spine
- Published
- 2025-02-20
- DOI
- https://doi.org/10.1002/jsp2.70051
- Citations
- 3
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 5.00
Funders
- HORIZON EUROPE Framework Programme
- HORIZON EUROPE European Research Council