Development and qualification of an LC-MS/MS method for quantification of MUC5AC and MUC5B mucins in spontaneous sputum
Our methodology provides accurate and reliable MUC5AC and MUC5B quantification and facilitates multi-site clinical sputum collection.
Authors
- Kushal Shah
- Catherine Huntington (ORCID: https://orcid.org/0000-0003-3193-9320)
- Neil E. Alexis (ORCID: https://orcid.org/0000-0002-9417-8269)
- Weiwen Sun (ORCID: https://orcid.org/0000-0002-8999-3103)
- Anton I. Rosenbaum (ORCID: https://orcid.org/0000-0003-1939-951X)
- William R. Mylott Jr (ORCID: https://orcid.org/0000-0001-7512-2131)
- Monica L. Gavala (ORCID: https://orcid.org/0000-0002-7475-3393)
- Jessica Larsson
- Helen Killick
- Si Mou
- Aaron Wheeler
- Kévin Contrepois (ORCID: https://orcid.org/0000-0001-9678-5161)
- Moucun Yuan (ORCID: https://orcid.org/0000-0001-7532-1296)
- Ian C. Scott (ORCID: https://orcid.org/0000-0003-4136-4751)
- Aoife Kelly
- Walter Wiley
- Mani Deepika Vakkalanka
Institutions
- University of North Carolina at Chapel Hill (US)
- AstraZeneca (Singapore) (SG)
- AstraZeneca (Brazil) (BR)
- Thermo Fisher Scientific (Israel) (IL)
Publication Details
- Journal
- Bioanalysis
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1080/17576180.2025.2457844
- Citations
- 3
- Primary Topic
- Glycosylation and Glycoproteins Research
- Type
- article
- Field-Weighted Citation Impact
- 2.42
Funders
- AstraZeneca