Efficacy of sivelestat in alleviating postoperative pulmonary injury in patients with acute aortic dissection undergoing total arch replacement: a retrospective cohort study
Among patients with AAD with mild or moderate preoperative lung injury, defined by a low P/F ratio, sivelestat significantly improved the postoperative P/F ratio and attenuated inflammatory responses after TAR. These findings suggest an important avenue for further research.
Authors
- Zhenxiao Jin (ORCID: https://orcid.org/0000-0003-0586-816X)
- Zhiyan Mai
- Weixun Duan (ORCID: https://orcid.org/0000-0003-4475-7067)
- Zheng Su (ORCID: https://orcid.org/0000-0002-3266-3373)
- Yang Chen (ORCID: https://orcid.org/0000-0002-4722-279X)
- Xudong Liu (ORCID: https://orcid.org/0000-0002-6893-8842)
- Tao Chen (ORCID: https://orcid.org/0000-0002-0613-2640)
- Yang Yang (ORCID: https://orcid.org/0000-0001-6417-3654)
- Jincheng Liu (ORCID: https://orcid.org/0000-0002-4903-6800)
- Yenong Zhou
Institutions
- Ministry of Education of the People's Republic of China (CN)
- Northwest University (CN)
- Ningxia Medical University (CN)
- Tang Du Hospital (CN)
- Xijing Hospital (CN)
- Air Force Medical University (CN)
Publication Details
- Journal
- BMC Cardiovascular Disorders
- Published
- 2025-02-20
- DOI
- https://doi.org/10.1186/s12872-025-04527-9
- Primary Topic
- Aortic Disease and Treatment Approaches
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China