Diallyl disulfide knee joint injection protects against the early pathologic changes of articular cartilage and subchondral bone in ovariectomized rats
These results suggest that DADS retards early OA progression in an OVX-OA rat model by improving cartilage metabolism and preventing the deterioration of subchondral bone microstructure, presenting a potential agent for ameliorating postmenopausal OA progression.
Authors
- Yun Tian (ORCID: https://orcid.org/0000-0003-2310-6054)
- Qizhao Tan (ORCID: https://orcid.org/0000-0003-0922-0467)
- Tengjiao Zhu (ORCID: https://orcid.org/0000-0002-2748-3773)
- Zhenda Zhao (ORCID: https://orcid.org/0000-0001-5237-6139)
- Zhongwei Yang (ORCID: https://orcid.org/0000-0002-4534-9922)
Institutions
- Ministry of Education of the People's Republic of China (CN)
- Peking University (CN)
- Ministry of Education (SA)
- Peking University Third Hospital (CN)
Publication Details
- Journal
- BMC Musculoskeletal Disorders
- Published
- 2025-02-20
- DOI
- https://doi.org/10.1186/s12891-025-08395-4
- Citations
- 2
- Primary Topic
- Garlic and Onion Studies
- Type
- article
- Field-Weighted Citation Impact
- 3.50
Funders
- AO Foundation
- National Natural Science Foundation of China
- Ministry of Science and Technology of the People's Republic of China
- Peking University
- Peking University Third Hospital