Upper limit of normothermic machine preservation of liver grafts from donation after circulatory death yet to be defined
Increased MPT of DCD liver grafts had no adverse recipient results for the times utilized in this population, indicating its upper limits, likely beyond 24 hours, are not demonstrated within this study. Future studies are necessary to determine whether longer MPT is beneficial or detrimental to graft function and, if the latter, what is the maximum safe duration. Further studies of the effect of normothermic machine perfusion pump duration on long-term outcomes are also needed.
Authors
- Roger Denny
- Allyson Cochran (ORCID: https://orcid.org/0000-0002-1213-0852)
- Katheryn Peterson
- José R. Soto (ORCID: https://orcid.org/0000-0001-8971-1623)
- E. Rein
- Chase J. Wehrle (ORCID: https://orcid.org/0000-0002-9275-4744)
- Vincent Casingal
- Lon Eskind
- W. Archie
- Maria Baimas‐George (ORCID: https://orcid.org/0000-0002-6649-4627)
- David Levi
- N. B. Haynes
- Souma Kundu
- Dionisios Vrochides
- D. Huckleberry
Institutions
- Cleveland Clinic (US)
- Carolinas Medical Center (US)
Publication Details
- Journal
- World Journal of Transplantation
- Published
- 2025-02-21
- DOI
- https://doi.org/10.5500/wjt.v15.i2.99170
- Citations
- 2
- Primary Topic
- Organ Transplantation Techniques and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 4.01