Clinical events and healthcare resource utilization associated with neutropenia and leukopenia among adult kidney transplant recipients receiving valganciclovir

Adults receiving valganciclovir and/or ganciclovir prophylaxis post-kidney transplantation had greater risk of neutropenia and/or leukopenia, which were associated with higher clinical event rates and HCRU up to 5 years post-transplantation. These findings suggest the need for alternative prophylaxis options with lower myelosuppressive effects to improve patient outcomes.

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Publication Details

Journal
World Journal of Transplantation
Published
2025-02-21
DOI
https://doi.org/10.5500/wjt.v15.i2.102671
Citations
1
Primary Topic
Cytomegalovirus and herpesvirus research
Type
article
Field-Weighted Citation Impact
1.35
Controls
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article

Clinical events and healthcare resource utilization associated with neutropenia and leukopenia among adult kidney transplant recipients receiving valganciclovir

Pamela Moise, Flavio Vincenti, Cheryl Xiang, Martha Pavlakis et al.
1 citations
World Journal of Transplantation
Cytomegalovirus and herpesvirus research
1.35
article

Clinical events and healthcare resource utilization associated with neutropenia and leukopenia among adult kidney transplant recipients receiving valganciclovir

Pamela Moise, Flavio Vincenti, Cheryl Xiang, Martha Pavlakis, Weijia Wang, Michael Wong, Wei Gao, Pangsibo Shen, A Beyer
article en
1 citations

Abstract

Adults receiving valganciclovir and/or ganciclovir prophylaxis post-kidney transplantation had greater risk of neutropenia and/or leukopenia, which were associated with higher clinical event rates and HCRU up to 5 years post-transplantation. These findings suggest the need for alternative prophylaxis options with lower myelosuppressive effects to improve patient outcomes.

World Journal of TransplantationVol. 15(2)
Analysis Group (United States) (US)
Openalex Percentile: Top 23%
Cytomegalovirus and herpesvirus research
1.35
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