Abnormal interbrain coupling in individuals with childhood adversity may underlie their difficulties in benefiting from social interactions

Among higher ACEs dyads, hyper interbrain coupling during distress may suggest heightened yet unsuccessful efforts to regulate distress, while hypo interbrain coupling in non-distressing situations may indicate poor connectedness in neutral social interactions. Therefore, abnormal interbrain coupling may underlie the difficulties high ACEs individuals face in benefiting from supportive interactions.