Interspecies differences in plasma protein binding of beta-lactam antibiotics
The study highlights substantial interspecies differences in the PPB of cefiderocol, ceftriaxone, and temocillin. The findings indicate the need for careful consideration of species-specific PPB in the optimisation of beta-lactam dosing and the development of new pharmaceuticals.
Authors
- Hifza Ahmed
- Christoph Dorn (ORCID: https://orcid.org/0000-0002-2560-9598)
- Markus Zeitlinger (ORCID: https://orcid.org/0000-0002-1873-3953)
Institutions
- University of Regensburg (DE)
- Medical University of Vienna (AT)
Publication Details
- Journal
- International Journal of Antimicrobial Agents
- Published
- 2025-02-21
- DOI
- https://doi.org/10.1016/j.ijantimicag.2025.107476
- Citations
- 1
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.59
Funders
- H2020 Marie Skłodowska-Curie Actions