Palladium-Catalyzed Intermolecular 1,3-Dienylation of Propargyl Esters Involving the Insertion of SO<sub>2</sub>
A palladium-catalyzed three-component 1,3-dienylation of propargylic esters with DABSO and aryl iodides has been developed. This novel reductive cross-coupling reaction produces 2-sufonylated 1,3-dienes as single products in the presence of reductive metal Mn with high regio- and chemoselectivities. Control experiments demonstrated that the transformation may undergo a radical process.
Authors
- Shuoshuo Zhang (ORCID: https://orcid.org/0000-0003-2092-4588)
- Ling Jin
- Yue Zhang (ORCID: https://orcid.org/0000-0002-2189-8580)
- Mengzhao Yu
- Xiaolei Huang (ORCID: https://orcid.org/0000-0001-7929-1987)
- Haohao Jiang
Institutions
- Zhejiang Normal University (CN)
Publication Details
- Journal
- Organic Letters
- Published
- 2025-02-20
- DOI
- https://doi.org/10.1021/acs.orglett.5c00334
- Citations
- 1
- Primary Topic
- Catalytic C–H Functionalization Methods
- Type
- article
- Field-Weighted Citation Impact
- 0.94