Use of rituximab and plasma exchange in treatment and prophylaxis of recurrent FSGS

We conclude that rituximab did not add significant benefit to plasma exchange when used as initial therapeutic intervention in post-transplant recurrent FSGS. The modest benefit of prophylactic therapies highlights the need for risk stratification to identify patients most likely to benefit from such interventions. Larger prospective studies with standardized approaches to treatment are essential in improving outcomes in rFSGS.

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Publication Details

Journal
Clinical Kidney Journal
Published
2025-02-20
DOI
https://doi.org/10.1093/ckj/sfaf058
Citations
1
Primary Topic
Systemic Sclerosis and Related Diseases
Type
article
Field-Weighted Citation Impact
1.47
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article

Use of rituximab and plasma exchange in treatment and prophylaxis of recurrent FSGS

Sophie Gharaei, Durga Kanigicherla, Omar Ragy, J Mahmoudi Gharaei
1 citations
Clinical Kidney Journal
Systemic Sclerosis and Related Diseases
1.47
article

Use of rituximab and plasma exchange in treatment and prophylaxis of recurrent FSGS

Sophie Gharaei, Durga Kanigicherla, Omar Ragy, J Mahmoudi Gharaei
article en
1 citations

Abstract

We conclude that rituximab did not add significant benefit to plasma exchange when used as initial therapeutic intervention in post-transplant recurrent FSGS. The modest benefit of prophylactic therapies highlights the need for risk stratification to identify patients most likely to benefit from such interventions. Larger prospective studies with standardized approaches to treatment are essential in improving outcomes in rFSGS.

Clinical Kidney JournalVol. 18(3)
Manchester Academic Health Science Centre (GB), University of Manchester (GB), Manchester VA Medical Center (US), Universidad Europea (MX), NIHR Manchester Biomedical Research Centre (GB), Universidad Europea de Madrid (ES)
Openalex Percentile: Top 23%
Systemic Sclerosis and Related Diseases
1.47
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Use of rituximab and plasma exchange in treatment and prophylaxis of recurrent FSGS — Sophie Gharaei, Durga Kanigicherla, et al. · Clinical Kidney Journal (2025) | TGRS Research Map | TGRS