Docetaxel rechallenge in HER2-negative metastatic breast cancer: a real-world study of previously discontinued patients for non-progression reasons

This study suggests that docetaxel rechallenge may be an effective and tolerable later-line treatment option for patients with HER2-negative MBC, particularly those who responded to initial DBT. However, further prospective, randomized controlled research is needed to fully evaluate its impact on disease response in this patient population.

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Publication Details

Journal
Journal of Cancer Research and Clinical Oncology
Published
2025-02-21
DOI
https://doi.org/10.1007/s00432-025-06133-w
Citations
1
Primary Topic
Cancer Treatment and Pharmacology
Type
article
Field-Weighted Citation Impact
1.05
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article

Docetaxel rechallenge in HER2-negative metastatic breast cancer: a real-world study of previously discontinued patients for non-progression reasons

Longgang Niu, Huimin Lv, Min Yan, Huihui Sun et al.
1 citations
Journal of Cancer Research and Clinical Oncology
Cancer Treatment and Pharmacology
1.05
article

Docetaxel rechallenge in HER2-negative metastatic breast cancer: a real-world study of previously discontinued patients for non-progression reasons

Longgang Niu, Huimin Lv, Min Yan, Huihui Sun, Jing Wang, Hao Zeng, Mengwei Zhang, Zhenzhen Liu
article en
1 citations

Abstract

This study suggests that docetaxel rechallenge may be an effective and tolerable later-line treatment option for patients with HER2-negative MBC, particularly those who responded to initial DBT. However, further prospective, randomized controlled research is needed to fully evaluate its impact on disease response in this patient population.

Journal of Cancer Research and Clinical OncologyVol. 151(2)
Zhengzhou University (CN), Henan Cancer Hospital (CN)
Good health and well-being
Openalex Percentile: Top 25%
Cancer Treatment and Pharmacology
1.05
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