Laparoscopic versus open parenchymal preserving liver resections in the posterosuperior segments (ORANGE Segments): a multicentre, single-blind, randomised controlled trial
This investigator-initiated trial was funded by Ethicon (Johnson & Johnson), Cancer Research United Kingdom, and Maastricht University Medical Centre+.
Authors
- Krishna Menon (ORCID: https://orcid.org/0000-0002-8193-4889)
- Mathieu D’Hondt (ORCID: https://orcid.org/0000-0001-5542-3017)
- Luca Aldrighetti (ORCID: https://orcid.org/0000-0001-7729-2468)
- John Primrose (ORCID: https://orcid.org/0000-0002-2069-7605)
- Mohammad Abu Hilal (ORCID: https://orcid.org/0000-0002-3162-4639)
- Céline De Meyere
- Marc G. Besselink (ORCID: https://orcid.org/0000-0003-2650-9350)
- Jasper P. Sijberden (ORCID: https://orcid.org/0000-0002-1186-5320)
- Robert S. Fichtinger (ORCID: https://orcid.org/0000-0002-9143-8213)
- Clarissa Ferrari (ORCID: https://orcid.org/0000-0002-4101-6872)
- Rafael Díaz-Nieto
- Somaiah Aroori (ORCID: https://orcid.org/0000-0002-5613-6463)
- Francesca Ratti (ORCID: https://orcid.org/0000-0002-8108-9064)
- Lloyd Brandts (ORCID: https://orcid.org/0000-0002-0620-1271)
- Михаил Ефанов (ORCID: https://orcid.org/0000-0003-0738-7642)
- Bram Olij (ORCID: https://orcid.org/0000-0002-1027-8685)
- Roberto Troisi (ORCID: https://orcid.org/0000-0001-6280-810X)
- Ronald M. van Dam (ORCID: https://orcid.org/0000-0001-8415-5090)
- Zina Eminton (ORCID: https://orcid.org/0009-0001-2747-4279)
- S. Pugh (ORCID: https://orcid.org/0000-0002-1866-8338)
- Robert P. Sutcliffe (ORCID: https://orcid.org/0000-0002-1881-7655)
- Christoph Kuemmerli (ORCID: https://orcid.org/0000-0002-7109-3545)
- Aali J. Sheen (ORCID: https://orcid.org/0000-0001-6054-5385)
- Zahir Soonawalla (ORCID: https://orcid.org/0000-0002-4213-4723)
- Rebecca Marino (ORCID: https://orcid.org/0000-0002-2069-6485)
- Ravi Marudanayagam (ORCID: https://orcid.org/0000-0002-0640-3535)
- Giuseppe Zimmitti
- Giuseppe Maria Ettorre
Institutions
- University of Jordan (JO)
- University Hospitals Birmingham NHS Foundation Trust (GB)
- University of Liverpool (GB)
- Vita-Salute San Raffaele University (IT)
- Maastricht University Medical Centre (NL)
- AZ Groeninge (BE)
- Oxford Health NHS Foundation Trust (GB)
- University Hospital of Basel (CH)
- Derriford Hospital (GB)
- University Hospital Southampton NHS Foundation Trust (GB)
- Ghent University (BE)
- Maastricht University (NL)
- University of Oxford (GB)
- Moscow Clinical Scientific Center (RU)
- Aintree University Hospital (GB)
- Manchester University NHS Foundation Trust (GB)
- Federico II University Hospital (IT)
- NIHR Southampton Biomedical Research Centre (GB)
- IRCCS San Camillo Hospital (IT)
- Fondazione Poliambulanza Istituto Ospedaliero (IT)
- Amsterdam University Medical Centers (NL)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- King's College Hospital (GB)
- Addenbrooke's Hospital (GB)
- Maastro Clinic (NL)
- University of Southampton (GB)
- Cancer Center Amsterdam (NL)
- Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele (IT)
- University of Amsterdam (NL)
- RWTH Aachen University (DE)
Publication Details
- Journal
- The Lancet Regional Health - Europe
- Published
- 2025-02-20
- DOI
- https://doi.org/10.1016/j.lanepe.2025.101228
- Citations
- 7
- Primary Topic
- Hepatocellular Carcinoma Treatment and Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 9.25
Funders
- University Hospital Southampton NHS Foundation Trust
- University Hospitals Birmingham NHS Foundation Trust
- University Hospitals Plymouth NHS Trust
- Amsterdam University Medical Centers
- Cancer Research UK
- King's College London
- University of Oxford
- Universiteit van Amsterdam
- Universiteit Maastricht
- Newcastle upon Tyne Hospitals NHS Foundation Trust
- Maastricht Universitair Medisch Centrum
- Universitetet i Oslo
- Ethicon