Health-related quality of life association with sociodemographic characteristics among children under-five with Down syndrome in Western Region Secondary Care Hospitals, Saudi Arabia

The level of HRQoL among children with DS was high, particularly in the physical and cognitive domains. The sociodemographic factors of parents, specifically the level of education and occupation of fathers, have been identified as essential factors influencing HRQoL. Providing increased economic and educational support for families has a significant positive impact on the quality of life for these children.