Enhancing breast cancer treatment: Evaluating the efficacy of hyaluronic acid-coated tamoxifen-loaded solid lipid nanoparticles on MCF7 cells
The in vitro release study showed that HA-coated SLNs consistently released the drug into the media under controlled conditions. Furthermore, HA-TMX-SLNs exhibited cytotoxic effects, increasing apoptosis and inhibiting cancer cell proliferation. These findings suggest that HA-TMX-SLNs effectively deliver TMX to breast cancer cells.
Authors
- Hossein Ghafouri (ORCID: https://orcid.org/0000-0003-2245-0697)
- Niloufar Ghayoumipour
Institutions
- University of Guilan (IR)
Publication Details
- Journal
- Human & Experimental Toxicology
- Published
- 2025-02-20
- DOI
- https://doi.org/10.1177/09603271251322531
- Citations
- 3
- Primary Topic
- Retinoids in leukemia and cellular processes
- Type
- article
- Field-Weighted Citation Impact
- 2.42