Screening and Validation of Potential Biomarkers of Immune Cells in Childhood Asthma Patients via Mendelian Randomization and Machine Learning
Our findings confirmed that immune cells contribute to childhood asthma, highlighting the importance of key genes in the role of the immune microenvironment in this disease. These insights provide a new path for the exploration of the biological underpinnings of childhood asthma and the development of early intervention therapies.
Authors
- Liangjia Cao (ORCID: https://orcid.org/0009-0008-6304-7806)
- Wenjuan Xu (ORCID: https://orcid.org/0009-0001-3096-3778)
- Hai Yang (ORCID: https://orcid.org/0000-0001-8937-4145)
- Jihong Hu (ORCID: https://orcid.org/0000-0001-8209-225X)
- Yang Zhang (ORCID: https://orcid.org/0009-0004-3433-1067)
- Jiaxuan Zhang (ORCID: https://orcid.org/0000-0002-7836-0394)
- Jing Xu (ORCID: https://orcid.org/0009-0004-7045-8161)
- Baifen Song
- Rukeye Yasen
Institutions
- Gansu University of Traditional Chinese Medicine (CN)
- Lanzhou University (CN)
Publication Details
- Journal
- Journal of Inflammation Research
- Published
- 2025-02-01
- DOI
- https://doi.org/10.2147/jir.s498017
- Citations
- 1
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 1.82