IgA Vasculitis (Henoch-Schönlein Purpura) in a Seven-Year-Old Female Child With Recurrent Respiratory Infections

A seven-year-old female child presented with a purpuric rash, joint pain, and a recent history of streptococcal pharyngitis. Initial symptoms included fever, throat pain, and vomiting, for which she received amoxicillin. Following treatment, the patient developed a rash and joint pain, prompting further evaluation. The physical examination revealed erythematous, edematous, and purpuric lesions on the extremities, along with periarticular swelling in the knees and ankles. Laboratory investigations showed hematuria, raising concerns for differential diagnoses, including IgA vasculitis, acute urticaria, acute glomerulonephritis, and idiopathic thrombocytopenic purpura. Treatment was adjusted with azithromycin and prednisolone. Despite these interventions, the patient's condition worsened, with new symptoms including fatigue, abdominal pain, and the spread of purpuric lesions. Although hospital admission was recommended, the patient's mother opted for care at an alternative facility. This case underscores the importance of early recognition and management of IgA vasculitis in pediatric patients and highlights potential links between prematurity and susceptibility to this condition.

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Publication Details

Journal
Cureus
Published
2025-02-20
DOI
https://doi.org/10.7759/cureus.79360
Primary Topic
Vasculitis and related conditions
Type
article
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0.00
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article

IgA Vasculitis (Henoch-Schönlein Purpura) in a Seven-Year-Old Female Child With Recurrent Respiratory Infections

Sheldon Padgett, MOHAMED SLEEM, Ahmed F. Rezk
Cureus
Vasculitis and related conditions
article

IgA Vasculitis (Henoch-Schönlein Purpura) in a Seven-Year-Old Female Child With Recurrent Respiratory Infections

Sheldon Padgett, MOHAMED SLEEM, Ahmed F. Rezk
article en

Abstract

A seven-year-old female child presented with a purpuric rash, joint pain, and a recent history of streptococcal pharyngitis. Initial symptoms included fever, throat pain, and vomiting, for which she received amoxicillin. Following treatment, the patient developed a rash and joint pain, prompting further evaluation. The physical examination revealed erythematous, edematous, and purpuric lesions on the extremities, along with periarticular swelling in the knees and ankles. Laboratory investigations showed hematuria, raising concerns for differential diagnoses, including IgA vasculitis, acute urticaria, acute glomerulonephritis, and idiopathic thrombocytopenic purpura. Treatment was adjusted with azithromycin and prednisolone. Despite these interventions, the patient's condition worsened, with new symptoms including fatigue, abdominal pain, and the spread of purpuric lesions. Although hospital admission was recommended, the patient's mother opted for care at an alternative facility. This case underscores the importance of early recognition and management of IgA vasculitis in pediatric patients and highlights potential links between prematurity and susceptibility to this condition.

CureusVol. 17(2)
Alabama College of Osteopathic Medicine (US)
Openalex Percentile: Top 95%
Vasculitis and related conditions
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IgA Vasculitis (Henoch-Schönlein Purpura) in a Seven-Year-Old Female Child With Recurrent Respiratory Infections — Sheldon Padgett, MOHAMED SLEEM, et al. · Cureus (2025) | TGRS Research Map | TGRS