Mitophagy is required to protect against excessive skeletal muscle atrophy following hindlimb immobilization
These findings emphasize the role of mitophagy in limiting excessive muscle atrophy during immobilization. Targeting mitophagy may offer new strategies to preserve muscle function during prolonged periods of immobilization.
Authors
- Albert Adam
- A. Russell Tupling (ORCID: https://orcid.org/0000-0002-3895-6767)
- Joe Quadrilatero (ORCID: https://orcid.org/0000-0002-9304-3557)
- Fasih A. Rahman (ORCID: https://orcid.org/0000-0003-4588-5378)
- Michelle M. Graham (ORCID: https://orcid.org/0000-0003-0708-7957)
- Emma Sara Juracic (ORCID: https://orcid.org/0000-0002-5353-0553)
Institutions
- University of Waterloo (CA)
Publication Details
- Journal
- Journal of Biomedical Science
- Published
- 2025-02-18
- DOI
- https://doi.org/10.1186/s12929-025-01118-w
- Citations
- 15
- Primary Topic
- Muscle Physiology and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 12.09
Funders
- Universities Space Research Association
- Natural Sciences and Engineering Research Council of Canada