Predicting lymph node metastases in three different vulvar squamous cell carcinoma subgroups
HPVneg/p53abn VSCCs have a higher risk of LNM compared to HPVpos VSCCs. HPVneg/p53wt VSCC are considered an intermediate risk group. Molecular subgroups contribute to LNM risk assessment at diagnosis. We developed a well-performing, clinically feasible model to predict the risk of LNM at diagnosis.
Authors
- Tjalling Bosse (ORCID: https://orcid.org/0000-0002-6881-8437)
- Mariëtte I.E. van Poelgeest (ORCID: https://orcid.org/0000-0001-5432-5001)
- Helena C. van Doorn (ORCID: https://orcid.org/0000-0003-1062-4485)
- Linda S. Nooij (ORCID: https://orcid.org/0000-0001-5741-4595)
- Anne Fleur van Velzen
- Kim E. Kortekaas
- Adam J Tulling
Institutions
- Leiden University Medical Center (NL)
- Willem-Alexander Kinderziekenhuis (NL)
- Erasmus MC Cancer Institute (NL)
Publication Details
- Journal
- Gynecologic Oncology
- Published
- 2025-02-20
- DOI
- https://doi.org/10.1016/j.ygyno.2025.02.008
- Citations
- 1
- Primary Topic
- Cervical Cancer and HPV Research
- Type
- article
- Field-Weighted Citation Impact
- 1.35