Fecal microbiota transplantation promotes functional recovery in mice with spinal cord injury by modulating the spinal cord microenvironment
FMT restored gut microbiota balance in SCI mice, mitigated inflammation, and promoted ECM remodeling, establishing an optimal environment for neural recovery. These findings demonstrated that FMT may represent a valuable approach to enhance functional recovery following SCI.
Authors
- Liyi Zhou
- Shun Yao (ORCID: https://orcid.org/0000-0002-0250-1656)
- Hui Zhang (ORCID: https://orcid.org/0000-0003-3293-2446)
- Zhizhong Li (ORCID: https://orcid.org/0000-0002-5934-5420)
- Huan Xie
- Zhilai Zhou (ORCID: https://orcid.org/0000-0001-6975-6314)
- Quanxin He
- Junjie Chen (ORCID: https://orcid.org/0000-0001-6371-3700)
Institutions
- Jinan University (CN)
- Guangdong Provincial People's Hospital (CN)
- First Affiliated Hospital of Jinan University (CN)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2025-02-20
- DOI
- https://doi.org/10.1186/s12967-025-06232-9
- Citations
- 6
- Primary Topic
- Pediatric Pain Management Techniques
- Type
- article
- Field-Weighted Citation Impact
- 20.96