Insight on the biomimetic of lysozyme interaction with functionalized iron oxide nanoparticles
Both formulations of IONPs demonstrate high affinity toward lysozyme proteins. This work shows a higher binding affinity between lysozyme and Thy-IONPs than with Cit-IONPs. These findings suggest that Thy-IONPs represent a promising class of nano-inhibitors for lysozyme, opening new avenues for treating disorders associated with lysozyme overexpression.
Authors
- Aly F. Mohamed (ORCID: https://orcid.org/0000-0002-0863-9496)
- Ahmed M. Elgharib (ORCID: https://orcid.org/0000-0001-6561-7472)
- Abdo A. Elfiky (ORCID: https://orcid.org/0000-0003-4600-6240)
- Wael M. Elshemey (ORCID: https://orcid.org/0000-0001-8103-9668)
Institutions
- Cairo University (EG)
- Iraqi University (IQ)
- Islamic University of Madinah (SA)
Publication Details
- Journal
- Therapeutic Delivery
- Published
- 2025-02-20
- DOI
- https://doi.org/10.1080/20415990.2025.2467029
- Citations
- 1
- Primary Topic
- Enzyme Structure and Function
- Type
- article
- Field-Weighted Citation Impact
- 0.52