Nickel-Catalyzed Decarbonylation of Aromatic Carboxylic Acids with P(O)-H<sub>(2)</sub> Compounds to Form C–P Bonds
A novel strategy for C-P bond formation has been developed. The reaction employed aromatic carboxylic acids as the source of aromatic groups to couple with three types of P(O)-H<sub>(2)</sub> compounds without the need to isolate intermediates, thereby achieving a one-pot construction of carbon-phosphorus bonds. The protocol demonstrated excellent applicability and functional group tolerance, enabling the production of Ar-P(O)R<sub>2</sub> and Ar<sub>2</sub>-PPh with moderate to excellent yields.
Authors
- Yongming Zhu (ORCID: https://orcid.org/0000-0002-7078-7908)
- Rui Tian (ORCID: https://orcid.org/0000-0001-5356-9944)
- Jia-Xin Li
Institutions
- Soochow University (TW)
Publication Details
- Journal
- The Journal of Organic Chemistry
- Published
- 2025-02-20
- DOI
- https://doi.org/10.1021/acs.joc.4c02554
- Citations
- 1
- Primary Topic
- Catalytic C–H Functionalization Methods
- Type
- article
- Field-Weighted Citation Impact
- 0.94
Funders
- Priority Academic Program Development of Jiangsu Higher Education Institutions