Characterisation of a COPD-associated nephronectin (<i>NPNT</i>) functional splicing genetic variant in human lung tissue<i>via</i>long-read sequencing
Genetic variants in the <i>NPNT</i> gene increase COPD risk by changing RNA splicing of <i>NPNT</i> in the lung.
Authors
- Silvia B. V. Ramos (ORCID: https://orcid.org/0000-0001-7900-9806)
- Christopher Vollmers (ORCID: https://orcid.org/0000-0002-7626-6222)
- Michael H. Cho (ORCID: https://orcid.org/0000-0002-4907-1657)
- Alain Laederach (ORCID: https://orcid.org/0000-0002-5088-9907)
- Lynn M. Schnapp
- Edwin K. Silverman (ORCID: https://orcid.org/0000-0002-3641-3822)
- Aabida Saferali (ORCID: https://orcid.org/0000-0001-6399-0249)
- Scott H. Randell (ORCID: https://orcid.org/0000-0001-5351-2841)
- Xiaobo Zhou (ORCID: https://orcid.org/0000-0002-7127-2869)
- Peter J. Castaldi (ORCID: https://orcid.org/0000-0001-9920-4713)
- Craig P. Hersh (ORCID: https://orcid.org/0000-0002-1342-4334)
- Gloria Sheynkman (ORCID: https://orcid.org/0000-0002-4223-9947)
- Zhonghui Xu (ORCID: https://orcid.org/0000-0002-6469-9178)
- Anastacia Wienecke
- Carole L. Wilson (ORCID: https://orcid.org/0000-0001-6692-0430)
- Tao Liu (ORCID: https://orcid.org/0000-0002-1182-991X)
Institutions
- University of North Carolina at Chapel Hill (US)
- Brigham and Women's Hospital (US)
- University of Wisconsin–Madison (US)
- University of California, Santa Cruz (US)
- University of Virginia (US)
Publication Details
- Journal
- European Respiratory Journal
- Published
- 2025-02-20
- DOI
- https://doi.org/10.1183/13993003.01407-2024
- Citations
- 4
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 3.22