Bio-3D printing of scaffold-free ADSC-derived cartilage constructs comparable to natural cartilage in vitro
By optimizing the cell culture conditions, inducing chondrogenic differentiation, and bio-3D printing, we successfully fabricated fully mature cartilage constructs with mechanical and histological properties similar to those of articular cartilage.
Authors
- Tadatsugu Morimoto (ORCID: https://orcid.org/0000-0002-3359-9684)
- Daiki Murata (ORCID: https://orcid.org/0000-0003-0201-0205)
- Koichi Nakayama (ORCID: https://orcid.org/0000-0002-7324-8862)
- Toshihiro Nonaka (ORCID: https://orcid.org/0009-0006-0261-5959)
- Hiromu Yoshizato (ORCID: https://orcid.org/0009-0004-7933-3744)
- Anna Nakamura (ORCID: https://orcid.org/0000-0003-3903-0306)
- S. Kashimoto (ORCID: https://orcid.org/0009-0000-2941-0116)
Institutions
- Saga University (JP)
Publication Details
- Journal
- Journal of Orthopaedic Surgery and Research
- Published
- 2025-02-20
- DOI
- https://doi.org/10.1186/s13018-025-05604-7
- Citations
- 8
- Primary Topic
- 3D Printing in Biomedical Research
- Type
- article
- Field-Weighted Citation Impact
- 5.39
Funders
- Japan Society for the Promotion of Science