Molecular Mechanism of Action of Abamectin on Human Microglia Clone 3 Cell Line

Introduction: Abamectin (ABA) is an insecticide that is commonly used in agricultural spraying. Although it is known to have neurotoxic effects on living organisms in the ecosystem and humans, the details of these effects, including the duration and amount of exposure, are not fully understood. The aim of this study is to evaluate the effect of ABA exposure on human microglia clone 3 (HMC3) cells. These cells were chosen because they are suitable for modeling immunological functions such as cytokine production, cell migration, and inflammation response.