Elderly patients are hyperresponsive to potent P2Y12 inhibitors
Patients aged ≥70 years on potent P2Y12 inhibitors exhibit increased inhibition of ADP-inducible platelet aggregation. In addition, elderly patients on prasugrel show a lower response to AA, collagen, SFLLRN and AYPGKF than younger patients.
Authors
- David Mutschlechner (ORCID: https://orcid.org/0000-0002-3189-6204)
- Patricia P. Wadowski (ORCID: https://orcid.org/0000-0003-2462-4515)
- Maximilian Tscharre (ORCID: https://orcid.org/0000-0002-9265-628X)
- Silvia Lee (ORCID: https://orcid.org/0000-0001-5405-9735)
- Joseph Pultar
- Thomas Gremmel (ORCID: https://orcid.org/0000-0001-9554-7292)
- Constantin Weikert
- Simon Panzer
Institutions
- Danube Private University (AT)
- Fachhochschule Wiener Neustadt (AT)
- Universitätsklinikum St. Pölten (AT)
- Landesklinikum Korneuburg (AT)
- Karl Landsteiner University of Health Sciences (AT)
- Karl Landsteiner Society (AT)
- Medical University of Vienna (AT)
Publication Details
- Journal
- Research and Practice in Thrombosis and Haemostasis
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1016/j.rpth.2025.102704
- Citations
- 3
- Primary Topic
- Cardiovascular Issues in Pregnancy
- Type
- article
- Field-Weighted Citation Impact
- 4.16