Assessing Autophagy Activation in Advanced Ovarian Cancer Using Ascitic Fluid: A Feasibility Study
Techniques for analyzing autophagy markers in ascitic fluid were successfully standardized. The ascitic fluid analysis offers a non-invasive, accessible method for studying ovarian cancer biology, potentially enhancing understanding and management. Further research with larger cohorts and integration of traditional biomarkers could improve clinical utility in ovarian cancer.
Authors
- Smita Kayal (ORCID: https://orcid.org/0000-0001-7275-7377)
- Alladi Charanraj Goud (ORCID: https://orcid.org/0000-0002-3355-7943)
- Medha Rajappa (ORCID: https://orcid.org/0000-0001-7725-9676)
- Biswajit Dubashi (ORCID: https://orcid.org/0000-0001-9852-2525)
- Luxitaa Goenka
- Debasis Gochhait (ORCID: https://orcid.org/0000-0002-3652-2076)
- Prabhu Manivannan (ORCID: https://orcid.org/0000-0001-8247-3343)
- L Charles
- Prasanth Ganesan (ORCID: https://orcid.org/0000-0003-2762-6591)
- Latha Chaturvedula (ORCID: https://orcid.org/0000-0002-6237-6551)
Institutions
- Jawaharlal Institute of Post Graduate Medical Education and Research (IN)
Publication Details
- Journal
- Cureus
- Published
- 2025-02-20
- DOI
- https://doi.org/10.7759/cureus.79371
- Primary Topic
- Autophagy in Disease and Therapy
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Jawaharlal Institute Of Postgraduate Medical Education and Research