Phosphorylated glycosphingolipids are commonly detected in Caenorhabditis elegans lipidomes

MassQL allowed us to search for phosphorylated glycosphingolipids and their potential biosynthetic precursors systematically. Using orthogonal information such as RT and CCS helped filter false positive results. With the detection in two different datasets, we demonstrate that these sphingolipids are a general part of the C. elegans lipidome.

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Publication Details

Journal
Metabolomics
Published
2025-02-20
DOI
https://doi.org/10.1007/s11306-024-02216-w
Citations
2
Primary Topic
Lipid metabolism and biosynthesis
Type
article
Field-Weighted Citation Impact
2.22
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article

Phosphorylated glycosphingolipids are commonly detected in Caenorhabditis elegans lipidomes

Michael A. Witting, Aiko Barsch, Liesa Salzer, Sven Meyer
2 citations
Metabolomics
Lipid metabolism and biosynthesis
2.22
article

Phosphorylated glycosphingolipids are commonly detected in Caenorhabditis elegans lipidomes

Michael A. Witting, Aiko Barsch, Liesa Salzer, Sven Meyer
article en
2 citations

Abstract

MassQL allowed us to search for phosphorylated glycosphingolipids and their potential biosynthetic precursors systematically. Using orthogonal information such as RT and CCS helped filter false positive results. With the detection in two different datasets, we demonstrate that these sphingolipids are a general part of the C. elegans lipidome.

MetabolomicsVol. 21(2)
Helmholtz Zentrum München (DE), Fahrenheit (Germany) (DE), Bruker (Germany) (DE), Leibniz-Institute for Food Systems Biology at the Technical University of Munich (DE), Technical University of Munich (DE)
Openalex Percentile: Top 15%
Lipid metabolism and biosynthesis
2.22
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Phosphorylated glycosphingolipids are commonly detected in Caenorhabditis elegans lipidomes — Michael A. Witting, Aiko Barsch, et al. · Metabolomics (2025) | TGRS Research Map | TGRS