Maternal age and the rising incidence of hypertensive disorders of pregnancy: A comprehensive analysis of national claims data from Japan
This study reveals that the risk of developing HDP is associated with both older childbearing and younger pregnancies and follows a J-curve, suggesting that factors other than maternal aging also contribute to the increased incidence of HDP and that further research on risk factors for HDP, which is on the rise worldwide, is urgently needed.
Authors
- Tasuku Mariya (ORCID: https://orcid.org/0000-0002-7110-980X)
- Tsuyoshi Saito (ORCID: https://orcid.org/0000-0001-9690-8440)
- Shintaro Takatsuka
- Masayuki Koyama (ORCID: https://orcid.org/0000-0002-8165-5855)
- Keisuke Oyatani (ORCID: https://orcid.org/0000-0002-7142-9432)
- Nobuaki Himuro (ORCID: https://orcid.org/0000-0003-2609-0510)
- Hirofumi Ohnishi (ORCID: https://orcid.org/0000-0002-5873-6438)
- Yoshika Kuno (ORCID: https://orcid.org/0000-0002-3965-5579)
- Shiro Hinotsu (ORCID: https://orcid.org/0009-0001-3111-695X)
- Naomi Maeda
Institutions
- Sapporo Medical University (JP)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-02-20
- DOI
- https://doi.org/10.1371/journal.pone.0319177
- Citations
- 3
- Primary Topic
- Pregnancy and preeclampsia studies
- Type
- article
- Field-Weighted Citation Impact
- 6.17
Funders
- Japan Society for the Promotion of Science