Mimicry-based strategy between human and commensal antigens for the development of a new family of immune therapies for cancer
These findings suggest that leveraging naturally occurring commensal-derived antigens through OMPs could significantly remodel the tumor immune landscape, offering guidance for a promising strategy for cancer peptide-based immunotherapies.
Authors
- Chloé Ventujol
- Alice Talpin
- Christophe Bonny (ORCID: https://orcid.org/0009-0006-8890-0290)
- Cécile Gouttefangeas (ORCID: https://orcid.org/0000-0002-6410-2378)
- María Vieito (ORCID: https://orcid.org/0000-0001-7531-343X)
- Coline Billerey
- Cheyenne Calderon (ORCID: https://orcid.org/0009-0006-1591-6769)
- Marine Malfroy
- Iris Mildenberger (ORCID: https://orcid.org/0009-0008-8825-4908)
- Michael C. Burger (ORCID: https://orcid.org/0000-0002-6927-0987)
- Catia Pereira Oliveira
- Julie Noguerol
- Laura Boullerot (ORCID: https://orcid.org/0000-0002-2029-4742)
- Alexandrine Garnier
- Karl Laviolette
- Guillaume Kulakowski
- François Ghiringhelli (ORCID: https://orcid.org/0000-0002-5465-8305)
- Olivier Joffre (ORCID: https://orcid.org/0000-0003-1168-8165)
- Camille Gaal (ORCID: https://orcid.org/0000-0001-7749-4609)
- Jérôme Kervevan (ORCID: https://orcid.org/0000-0002-5070-022X)
- Laurent Chêne
- Francesco Strozzi (ORCID: https://orcid.org/0000-0002-6845-6982)
- David A. Reardon (ORCID: https://orcid.org/0000-0001-6674-0157)
- Olivier Adotévi (ORCID: https://orcid.org/0000-0002-7742-136X)
- Agostina Stradella (ORCID: https://orcid.org/0000-0002-2307-8869)
- Ulrich Herrlinger (ORCID: https://orcid.org/0000-0002-4011-9327)
- Lucie Aubergeon (ORCID: https://orcid.org/0000-0002-3459-7904)
- Ludivine Amable
- João G. Magalhães (ORCID: https://orcid.org/0000-0003-4667-605X)
- Tifanny Mersceman
- Wolfgang Wick (ORCID: https://orcid.org/0000-0002-6171-634X)
- Jean-Marie Carpier
- Ghazaleh Tabatabai (ORCID: https://orcid.org/0000-0002-3542-8782)
- Diana Bachrouche
- Ahmed Idbaïh (ORCID: https://orcid.org/0000-0001-5290-1204)
- Ana Maia (ORCID: https://orcid.org/0000-0003-1261-7211)
- Jennifer Martinez
- Grégoire Chevalier (ORCID: https://orcid.org/0000-0003-4698-1206)
- Léa Bernard
- Michaël Bonnet
- Amandine Manteau
Institutions
- Goethe University Frankfurt (DE)
- Centre National de la Recherche Scientifique (FR)
- Université Toulouse III - Paul Sabatier (FR)
- Inserm (FR)
- University of Mannheim (DE)
- Université Fédérale de Toulouse Midi-Pyrénées (FR)
- German Cancer Research Center (DE)
- Heidelberg University (DE)
- University Hospital Bonn (DE)
- University Hospital Heidelberg (DE)
- Sorbonne Université (FR)
- Centre Georges François Leclerc (FR)
- Assistance Publique – Hôpitaux de Paris (FR)
- Toulouse Mathematics Institute (FR)
- Enterome (France) (FR)
- Dana-Farber Cancer Institute (US)
- Vall d'Hebron Hospital Universitari (ES)
- University Hospital Frankfurt (DE)
- Hertie Institute for Clinical Brain Research (DE)
- Duran i Reynals Hospital (ES)
- University of Tübingen (DE)
- Université de Franche-Comté (FR)
Publication Details
- Journal
- Journal for ImmunoTherapy of Cancer
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1136/jitc-2024-010192
- Citations
- 3
- Primary Topic
- Immunotherapy and Immune Responses
- Type
- article
- Field-Weighted Citation Impact
- 2.39
Funders
- Université de Lausanne
- Sorbonne Université