Impact of Relapse in BDNF Receptors Expression in Patients With a First Episode of Schizophrenia
These findings highlight the biological impact that a relapse produces over the systemic BDNF-TrkB signaling pathway, potentially undermining crucial neuronal functions. Identifying the actors involved can help design specific interventions for relapse prevention and improve the functional prognosis of people in the early stages of schizophrenia.
Authors
- Karina S. MacDowell (ORCID: https://orcid.org/0000-0002-1527-8895)
- Manuel J. Cuesta (ORCID: https://orcid.org/0000-0003-0250-5718)
- Ángela Ibáñez (ORCID: https://orcid.org/0000-0003-2751-0150)
- Anna Mané (ORCID: https://orcid.org/0000-0003-2127-349X)
- Miquel Bernardo (ORCID: https://orcid.org/0000-0001-8748-6717)
- Rafael Segarra (ORCID: https://orcid.org/0000-0002-2033-8151)
- Covadonga M. Díaz‐Caneja (ORCID: https://orcid.org/0000-0001-8538-3175)
- Ana González‐Pinto (ORCID: https://orcid.org/0000-0002-2568-5179)
- Albert Martínez-Pinteño (ORCID: https://orcid.org/0000-0003-2035-5979)
- Gisela Mezquida (ORCID: https://orcid.org/0000-0002-6080-2203)
- Sílvia Amoretti (ORCID: https://orcid.org/0000-0001-6017-2734)
- Esther Berrocoso (ORCID: https://orcid.org/0000-0003-0208-7472)
- Pilar A. Sáiz (ORCID: https://orcid.org/0000-0002-5705-4523)
- Miquel Bioque (ORCID: https://orcid.org/0000-0001-6887-7149)
- António Lobo (ORCID: https://orcid.org/0000-0002-9098-655X)
- Vicent Llorca-Bofí
- Alexandra Roldán
- Guillermo Cano-Escalera
Institutions
- Universidad Complutense de Madrid (ES)
- Universitat Autònoma de Barcelona (ES)
- Universidad de Oviedo (ES)
- Universitat Pompeu Fabra (ES)
- Universidad de Alcalá (ES)
- Universidad de Zaragoza (ES)
- Instituto de Salud Carlos III (ES)
- Hospital de Sant Pau (ES)
- Hospital General Universitario Gregorio Marañón (ES)
- Universidad de Cádiz (ES)
- Research Institute Hospital 12 de Octubre (ES)
- BioCruces Health research Institute (ES)
- Centro de Investigación Biomédica en Red de Salud Mental (ES)
- Vall d'Hebron Institut de Recerca (ES)
- Hospital Universitario Araba (ES)
- Navarre Institute of Health Research (ES)
- Neuroscience Institute (IT)
- Hospital Clínic de Barcelona (ES)
- Biomedical Research and Innovation Institute of Cadiz (ES)
- Instituto Ramón y Cajal de Investigación Sanitaria (ES)
- Vall d'Hebron Hospital Universitari (ES)
- Hospital Del Mar (ES)
- Parc de Salut (ES)
- Instituto de Investigación Sanitaria Aragón (ES)
- Hospital de Cruces (ES)
- Biomedical Research Institute (US)
- Hospital Universitario Puerta del Mar (ES)
- Hospital del Mar Research Institute (ES)
- Consorci Institut D'Investigacions Biomediques August Pi I Sunyer (ES)
- Hospital Universitario Ramón y Cajal (ES)
- Medical Research Network (US)
- Instituto de Investigación Sanitaria del Principado de Asturias (ES)
- Universitat de Barcelona (ES)
- Universidad de Navarra (ES)
Publication Details
- Journal
- Schizophrenia Bulletin
- Published
- 2025-02-20
- DOI
- https://doi.org/10.1093/schbul/sbaf012
- Primary Topic
- Autism Spectrum Disorder Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Instituto de Salud Carlos III