Adverse Events during a 12-Month Multisite Dose–Response Aerobic Exercise Intervention
While aerobic exercise increased the risk of intervention-related AE, the overall risk of all-cause AEs was not found to be different across exercise intensities. Higher adherence to the exercise regimen was associated with fewer AE. These findings suggest aerobic exercise is generally safe in older adults, with the benefits outweighing the risks.
Authors
- Kirk I. Erickson (ORCID: https://orcid.org/0000-0001-8736-981X)
- George Grove (ORCID: https://orcid.org/0000-0002-5043-139X)
- Arthur Kramer (ORCID: https://orcid.org/0000-0002-1991-5046)
- Eric D. Vidoni (ORCID: https://orcid.org/0000-0001-5181-7131)
- Edward McAuley (ORCID: https://orcid.org/0000-0002-4574-3292)
- John M. Jakicic (ORCID: https://orcid.org/0000-0001-6800-9368)
- Mickeal N. Key (ORCID: https://orcid.org/0000-0002-7535-0107)
- Charles H. Hillman (ORCID: https://orcid.org/0000-0002-3722-5612)
- Amanda N. Szabo‐Reed (ORCID: https://orcid.org/0000-0002-4927-1501)
- Jeffrey Murray Burns (ORCID: https://orcid.org/0000-0001-7609-8954)
- Tami L. Thomas (ORCID: https://orcid.org/0000-0002-3907-1899)
- Haiqing Huang (ORCID: https://orcid.org/0000-0002-8932-7995)
- Chaeryon Kang (ORCID: https://orcid.org/0000-0001-9442-8515)
- Lu Wan (ORCID: https://orcid.org/0000-0001-8939-3004)
- Sydney White
Institutions
- Northeastern University (US)
- University of Illinois Urbana-Champaign (US)
- University of Pittsburgh (US)
- University of Kansas Medical Center (US)
- S.P.E.C.I.E.S. (US)
Publication Details
- Journal
- Exercise Sport and Movement
- Published
- 2025-02-20
- DOI
- https://doi.org/10.1249/esm.0000000000000045
- Primary Topic
- Cardiovascular and exercise physiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- University of Pittsburgh
- National Institutes of Health