[Prevalence of common chronic diseases and related factors in HIV-infected persons in Henan Province, 2023].
<b>Objective:</b> To understand the prevalence and related factors of three common chronic diseases, hyperlipidemia, hypertension and diabetes in HIV-infected persons. <b>Methods:</b> As of December 2023, HIV-infected persons >15 years old who are receiving antiviral therapy (ART) and follow-up in Henan Province were selected as the study objects. Questionnaires, physical examinations, and blood samples were collected to collect demographic information, ART, body weight, blood lipids, blood pressure, and blood sugar of HIV-infected persons. The logistic regression model was used to analyze the related factors of hyperlipidemia, hypertension and diabetes. <b>Results:</b> Among 4 023 HIV-infected patients, the prevalence rates of hyperlipidemia, hypertension, and diabetes were 64.47% (2 594/4 023), 16.80% (676/4 023), and 10.54% (424/4 023), respectively. Multivariate analysis showed that hyperlipidemia was positively associated with ≥40 years of age, overweight and obesity, two nucleoside reverse transcriptase inhibitors (NRTIs) + proteasome inhibitors (PIs) regimen and two NRTIs+ integrase inhibitor regimen, and negatively associated with low body weight. Hypertension was positively correlated with the age group ≥40 years old, family history of cardiovascular and cerebrovascular diseases, overweight and obesity, ART time ≥0.5 years, and negatively correlated with low body weight. Diabetes was positively associated with age group ≥40 years, family history of cardiovascular and cerebrovascular disease, overweight and obesity, and negatively associated with the use of two NRTIs+PIs treatment regimens. <b>Conclusions:</b> In 2023, the prevalence of hyperlipidemia, hypertension, and diabetes among HIV-infected people in Henan Province was relatively high, and the risk of common chronic diseases among those ≥40 years old, overweight and obese, and those with a family history of cardiovascular and cerebrovascular diseases was also relatively high. It is recommended to strengthen the prevention and management of common chronic diseases among HIV-infected people.
Authors
- Z Y Chen (ORCID: https://orcid.org/0009-0007-5942-3103)
- Q Li
- Yehuan Sun (ORCID: https://orcid.org/0000-0002-8651-8059)
- Xuan Yang (ORCID: https://orcid.org/0000-0002-1921-8929)
- Mario C. Deng (ORCID: https://orcid.org/0000-0002-5202-3816)
- Suxian Zhao (ORCID: https://orcid.org/0000-0001-6674-4721)
- Z H Zhang
- Chao Liu (ORCID: https://orcid.org/0000-0002-3643-3903)
- Q X Zhao
- Mengjia Hou
Institutions
- Henan Provincial People's Hospital (CN)
- The Sixth People's Hospital of Zhengzhou (CN)
Publication Details
- Journal
- PubMed
- Published
- 2025-02-10
- DOI
- https://doi.org/10.3760/cma.j.cn112338-20240626-00375
- Primary Topic
- HIV-related health complications and treatments
- Type
- article