Unique Nerve Tissue‐Restricted T‐Cell Clones in Chronic Inflammatory Demyelinating Polyneuropathy

Unique nerve tissue-restricted TCRβ clones may indicate a highly localized immune response with localized expansion and/or retention of T-cells that could contribute to the pathomechanism of CIDP. Further characterization of the phenotype, antigen target and functionality of these T-cells is essential to determine their pathogenic role.

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Publication Details

Journal
Journal of the Peripheral Nervous System
Published
2025-02-18
DOI
https://doi.org/10.1111/jns.70006
Citations
1
Primary Topic
Peripheral Neuropathies and Disorders
Type
article
Field-Weighted Citation Impact
1.39

Funders

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Unique Nerve Tissue‐Restricted T‐Cell Clones in Chronic Inflammatory Demyelinating Polyneuropathy

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article

Unique Nerve Tissue‐Restricted T‐Cell Clones in Chronic Inflammatory Demyelinating Polyneuropathy

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article en
1 citations

Abstract

Unique nerve tissue-restricted TCRβ clones may indicate a highly localized immune response with localized expansion and/or retention of T-cells that could contribute to the pathomechanism of CIDP. Further characterization of the phenotype, antigen target and functionality of these T-cells is essential to determine their pathogenic role.

Journal of the Peripheral Nervous SystemVol. 30(1)
Sanquin (NL), St. Antonius Ziekenhuis (NL), Amsterdam University Medical Centers (NL), Spaarne Gasthuis (NL), University of Amsterdam (NL)
Prinses Beatrix Spierfonds
Good health and well-being
Openalex Percentile: Top 23%
Peripheral Neuropathies and Disorders
1.39
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