Biological dose‐based fractional dose optimization of Bragg peak FLASH‐RT for lung cancer treatment
Bragg peak FLASH-RT achieved high dose conformality for both peripheral and central tumors. Fractional dose optimization, using a single beam per fraction delivery mode, enhanced normal tissue sparing by leveraging both fractionation and FLASH effects.
Authors
- Y. Zeng (ORCID: https://orcid.org/0000-0003-2145-3458)
- Shuoyan Chen
- Zhiyong Yang (ORCID: https://orcid.org/0000-0002-2806-1214)
- Bin Qin (ORCID: https://orcid.org/0000-0001-5082-7805)
- Muyu Liu (ORCID: https://orcid.org/0000-0003-2262-8950)
- Qi Zhang (ORCID: https://orcid.org/0009-0004-4089-4552)
- Xu Liu (ORCID: https://orcid.org/0000-0002-9067-3393)
- Wei Wang (ORCID: https://orcid.org/0000-0002-0284-8414)
- Bo Pang (ORCID: https://orcid.org/0009-0000-5239-3852)
- Hong Quan (ORCID: https://orcid.org/0000-0003-3510-3854)
- Yu Chang
Institutions
- Union Hospital (HK)
- Wuhan University (CN)
- Wuhan Union Hospital (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Medical Physics
- Published
- 2025-02-18
- DOI
- https://doi.org/10.1002/mp.17697
- Citations
- 2
- Primary Topic
- Radiation Therapy and Dosimetry
- Type
- article
- Field-Weighted Citation Impact
- 3.04