Extracellular Vesicles Derived From Lipopolysaccharide‐Challenged Gingival Fibroblast Reveal Distinct miRNA Expression Patterns Associated With Reduced Cancer Survival
LPS stimulation alters the miRNA cargo of gingival fibroblast-derived EVs, enhancing pathways associated with inflammation and cancer progression. These findings suggest a mechanistic role for periodontal EVs in systemic disease pathogenesis, warranting further investigation into their diagnostic and therapeutic potential.
Authors
- Daniel Pembaur
- Daniel Diehl (ORCID: https://orcid.org/0000-0002-5809-3823)
- C. Brauer
- Anton Friedmann (ORCID: https://orcid.org/0000-0002-8708-829X)
- Patrick Philipp Weil (ORCID: https://orcid.org/0000-0002-6394-4274)
- Hagen S. Bachmann (ORCID: https://orcid.org/0000-0002-8642-540X)
Institutions
- Witten/Herdecke University (DE)
Publication Details
- Journal
- Clinical and Experimental Dental Research
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1002/cre2.70099
- Citations
- 2
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 1.61