Outcomes of <scp>BCG</scp> vs upfront radical cystectomy for high‐risk non‐muscle‐invasive bladder cancer
Within a European cohort of patients with HR- and VHR-NMIBC, upfront RC was rarely performed. Patients treated with BCG did not exhibit a CSM disadvantage relative to their upfront RC counterparts. After matching, long-term CSM was similar between BCG therapy and upfront RC. Delayed RC, led to worse outcomes if performed after progression, but matched upfront RC when performed before progression, underscoring importance of timely surgery.
Authors
- Roberto Contieri (ORCID: https://orcid.org/0000-0001-7011-0537)
- Laura S. Mertens (ORCID: https://orcid.org/0000-0003-3317-6427)
- Francesco Soria (ORCID: https://orcid.org/0000-0001-8443-8453)
- Wojciech Krajewski (ORCID: https://orcid.org/0000-0003-1727-2283)
- Pietro Scilipoti (ORCID: https://orcid.org/0009-0007-6126-9889)
- David D‘Andrea (ORCID: https://orcid.org/0000-0003-1625-1077)
- Riccardo Mastroianni (ORCID: https://orcid.org/0000-0003-3708-2209)
- Ekaterina Laukhtina
- Paolo Gontero (ORCID: https://orcid.org/0000-0002-9714-6596)
- Aleksander Ślusarczyk (ORCID: https://orcid.org/0000-0002-4344-0191)
- Luca Afferi (ORCID: https://orcid.org/0000-0002-5472-1933)
- Alberto Briganti (ORCID: https://orcid.org/0000-0002-2178-0494)
- Andrea Gallioli (ORCID: https://orcid.org/0000-0002-3316-5691)
- Javier Aranda (ORCID: https://orcid.org/0000-0002-9000-6670)
- Keiichiro Mori (ORCID: https://orcid.org/0000-0002-6147-6569)
- Andrea Salonia (ORCID: https://orcid.org/0000-0002-0595-7165)
- Mattia Longoni (ORCID: https://orcid.org/0000-0002-2613-2306)
- Giuseppe Simone (ORCID: https://orcid.org/0000-0002-4868-9025)
- José Luis Rodríguez Elena
- Simone Albisinni (ORCID: https://orcid.org/0000-0001-5529-3064)
- Francesco Montorsi (ORCID: https://orcid.org/0000-0002-7267-4181)
- Mario de Angelis (ORCID: https://orcid.org/0009-0008-0494-7839)
- Gautier Marcq (ORCID: https://orcid.org/0000-0002-1806-1448)
- Morgan Rouprêt (ORCID: https://orcid.org/0000-0001-8440-7075)
- J. Caño Velasco
- José Daniel Subiela (ORCID: https://orcid.org/0000-0003-4176-8174)
- Renate Pichler (ORCID: https://orcid.org/0000-0001-5286-9048)
- Rodolfo Hurle (ORCID: https://orcid.org/0000-0001-9978-8587)
- Andrea Necchi (ORCID: https://orcid.org/0000-0002-3007-2756)
- Marco Moschini (ORCID: https://orcid.org/0000-0002-3084-2458)
- Benjamin Pradere
- Paolo Zaurito
- A. Lafuente Puentedura
- Katharina Oberneder
- Andrea Mari (ORCID: https://orcid.org/0000-0001-9070-5706)
- Francesco Del Giudice (ORCID: https://orcid.org/0000-0003-3865-5988)
- Shahrokh F Shariat
- Piotr Radziszewski
Institutions
- Jikei University School of Medicine (JP)
- University of Rome Tor Vergata (IT)
- Universitat Autònoma de Barcelona (ES)
- Humanitas University (IT)
- Innsbruck Medical University (AT)
- Vita-Salute San Raffaele University (IT)
- Universidad de Alcalá (ES)
- Universität Innsbruck (AT)
- Cornell University (US)
- Charles University (CZ)
- Medical University of Warsaw (PL)
- Policlinico Umberto I (IT)
- The Netherlands Cancer Institute (NL)
- Hospital General Universitario Gregorio Marañón (ES)
- Centre Hospitalier Universitaire de Lille (FR)
- Wroclaw Medical University (PL)
- Sorbonne Université (FR)
- Comprehensive Cancer Center Vienna (AT)
- Assistance Publique – Hôpitaux de Paris (FR)
- Azienda Ospedaliero Universitaria San Giovanni Battista (IT)
- Azienda Ospedaliero-Universitaria Careggi (IT)
- Luzerner Kantonsspital (CH)
- Pitié-Salpêtrière Hospital (FR)
- Instituto Ramón y Cajal de Investigación Sanitaria (ES)
- IRCCS Ospedale San Raffaele (IT)
- Puigvert Foundation (ES)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- Hôpital Claude Huriez (FR)
- Complejo Hospitalario de Cáceres (ES)
- Karl Landsteiner Society (AT)
- Hospital Universitario Ramón y Cajal (ES)
- Onco-Urologie Prédictive (FR)
- University of Florence (IT)
- Medical University of Vienna (AT)
- Sapienza University of Rome (IT)
- The University of Texas Southwestern Medical Center (US)
Publication Details
- Journal
- British Journal of Urology
- Published
- 2025-02-18
- DOI
- https://doi.org/10.1111/bju.16675
- Citations
- 10
- Primary Topic
- Bladder and Urothelial Cancer Treatments
- Type
- article
- Field-Weighted Citation Impact
- 20.06