Diagnostic Value of ADC in Distinguishing Endometrial Cancer from Atypical Endometrial Hyperplasia and Within Molecular Subtypes

This retrospective study demonstrated that ADC, especially when combined with age and fibrinogen, is a valuable biomarker for distinguishing EC from AEH. In addition to indicating the Ki-67 index and histological grade, ADC values also serve as a promising tool for identifying the NSMP subtype within EC. Future studies should focus on multi-center, prospective studies with larger sample sizes to validate and refine the diagnostic value of ADC in differentiating EC from AEH, as well as in the molecular classification of EC.

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Publication Details

Journal
International Journal of Women s Health
Published
2025-02-01
DOI
https://doi.org/10.2147/ijwh.s501413
Citations
1
Primary Topic
Endometrial and Cervical Cancer Treatments
Type
article
Field-Weighted Citation Impact
2.06
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article

Diagnostic Value of ADC in Distinguishing Endometrial Cancer from Atypical Endometrial Hyperplasia and Within Molecular Subtypes

Xuemei Jia, Juan Xu, Reham Mohamed, Yao Yao et al.
1 citations
International Journal of Women s Health
Endometrial and Cervical Cancer Treatments
2.06
article

Diagnostic Value of ADC in Distinguishing Endometrial Cancer from Atypical Endometrial Hyperplasia and Within Molecular Subtypes

Xuemei Jia, Juan Xu, Reham Mohamed, Yao Yao, Yun Gu, Shengjie Xu, Wenwei Tang
article en
1 citations

Abstract

This retrospective study demonstrated that ADC, especially when combined with age and fibrinogen, is a valuable biomarker for distinguishing EC from AEH. In addition to indicating the Ki-67 index and histological grade, ADC values also serve as a promising tool for identifying the NSMP subtype within EC. Future studies should focus on multi-center, prospective studies with larger sample sizes to validate and refine the diagnostic value of ADC in differentiating EC from AEH, as well as in the molecular classification of EC.

International Journal of Women s HealthVol. Volume 17
Nanjing Children's Hospital (CN), Nanjing Maternity and Child Health Care Hospital (CN), Nanjing Medical University (CN)
Openalex Percentile: Top 18%
Endometrial and Cervical Cancer Treatments
2.06
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Diagnostic Value of ADC in Distinguishing Endometrial Cancer from Atypical Endometrial Hyperplasia and Within Molecular Subtypes — Xuemei Jia, Juan Xu, et al. · International Journal of Women s Health (2025) | TGRS Research Map | TGRS