Study on the mechanism of action of berberine combined with Jianpi Yishen Huazhuo formulation in treating obese polycystic ovary syndrome by activating PI3K/AKT signaling pathway
Berberine combined with JPYSHZF can improve the sex hormone levels, ovarian function, glucose and lipid metabolism levels, and gastrointestinal hormone levels in obese PCOS rats by activating the PI3K/AKT signaling pathway, thereby playing a role in treating obese PCOS.
Authors
- Lijun Liang
- Ya-Hong Feng
- Gaxi Ye
- Dejiang Ji
- Xiao‐Jing Zhang (ORCID: https://orcid.org/0000-0002-8271-7405)
- Yan Zhang (ORCID: https://orcid.org/0000-0003-2326-2225)
- Chen Du
- Aqsa Ahmad
Institutions
- Ningxia Medical University (CN)
- Ningxia Medical University General Hospital (CN)
Publication Details
- Journal
- Gynecological Endocrinology
- Published
- 2025-02-18
- DOI
- https://doi.org/10.1080/09513590.2025.2462068
- Citations
- 5
- Primary Topic
- Ovarian function and disorders
- Type
- article
- Field-Weighted Citation Impact
- 8.49
Funders
- Natural Science Foundation of Ningxia Province