Prevalence and Spectrum of Neuropathies in a Cohort of 585 Patients With Immunoglobulin A Monoclonal Gammopathy

In patients with IgA gammopathy, neuropathies have a low prevalence and a wide etiological spectrum. AL amyloidosis and POEMS syndrome are rare but crucial to identify, as disease-modifying treatments are available. Future studies should help better characterize the rare cases of neuropathy with an uncertain relationship to IgA gammopathy.

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Publication Details

Journal
European Journal of Neurology
Published
2025-02-01
DOI
https://doi.org/10.1111/ene.70087
Primary Topic
Peripheral Neuropathies and Disorders
Type
article
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article

Prevalence and Spectrum of Neuropathies in a Cohort of 585 Patients With Immunoglobulin A Monoclonal Gammopathy

Valentine Perrain, Jehan Dupuis, Jean‐Pascal Lefaucheur, Valérie Molinier‐Frenkel et al.
European Journal of Neurology
Peripheral Neuropathies and Disorders
article

Prevalence and Spectrum of Neuropathies in a Cohort of 585 Patients With Immunoglobulin A Monoclonal Gammopathy

Valentine Perrain, Jehan Dupuis, Jean‐Pascal Lefaucheur, Valérie Molinier‐Frenkel, Alain Créange, Thierry Gendre
article en

Abstract

In patients with IgA gammopathy, neuropathies have a low prevalence and a wide etiological spectrum. AL amyloidosis and POEMS syndrome are rare but crucial to identify, as disease-modifying treatments are available. Future studies should help better characterize the rare cases of neuropathy with an uncertain relationship to IgA gammopathy.

European Journal of NeurologyVol. 32(2)
Université Paris-Est Créteil (FR), Hôpitaux Universitaires Henri-Mondor (FR)
Openalex Percentile: Top 95%
Peripheral Neuropathies and Disorders
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